How Phenylethylamine HCL Helps : Phenylethylamine is a naturally occurring amine alkaloid which is derived from an amino acid phenylalanine. This compound is commonly regarded as a neuromodulator because it regulates the release of many neurotransmitters in the body. It’s actively involved in many bodily functions like mood regulation, cognitive enhancement, weight loss, prevention of psychological disorders like depression, anxiety and more. Phenylethylamine HCL is a commonly available form of phenylethylamine which is used as an oral supplement to obtain many health benefits.
Let’s take a look at the mechanisms through which phenylethylamine works to perform these functions.
Action of Phenylethylamine for Mood Regulation
Phenylethylamine easily crosses the blood brain barrier and enters our CNS i.e. central nervous system. Once it enters the CNS, phenylethylamine is involved in the release of a number of brain chemicals. It increases the release of an opioid peptide b-endorphin which is greatly associated with the feelings of pleasure and well-being in an individual. In addition to this, phenylethylamine also causes an increased release of two neurotransmitters i.e. norepinephrine and dopamine. Both of these neurotransmitters are majorly involved in uplifting the mood and generating the feelings of euphoria.
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Because of causing an increased release of b-endorphins, dopamine and norepinephrine which are the major components for mood regulation, phenylethylamine is also helpful in treating psychological disorders like depression, anxiety and mania. Phenylethylamine is a common ingredient of a number of anti-depressants and anxiolytic medicines.
This compound also acts as a potent vasoconstrictor which means that it cause the constriction or shrinkage of blood vessels. Because of this reason, phenylethylamine causes an increase in blood pressure and blood sugar levels. A mildly elevated blood pressure and glucose level in the body decreases the sensations of fatigue and lethargy and a person feels energized and refreshed. This phenomenon is also helpful in decreasing the feelings of depression and hopelessness.
However, this compound shouldn’t be consumed by patients suffering from hypertension or any other cardiovascular disorder like myocardial infarction or angina, because the increasing blood pressure can worsen these medical conditions.
How Phenylethylamine HCL Helps In Weight Loss
Phenylethylamine causes weight loss in an individual via two mechanisms. Firstly, this compound causes an increased release of catecholamines i.e. dopamine and norepinephrine; both of these chemicals are actively involved in stimulating the process of lipolysis i.e. fat breakdown in the body. Because of lipolysis, the stored fat of the body is released and consumed, which causes weight loss in an individual.
Secondly, mood-swings, depression and anxiety usually lead to a habit called ‘comfort eating’ in which a person faces an irresistible urge to eat all the time. This habit can lead to excessive weight gain in an individual. When these conditions are prevented or treated by phenylethylamine because of the release of mood-regulating chemicals, a person doesn’t suffer from the harmful habit of comfort eating and their weight is maintained.
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Phenylethylamine also improves the overall metabolism of the body and curbs the appetite which further helps in causing weight loss in an individual.
There are two drawbacks associated with phenylethylamine HCL. Phenylethylamine is rapidly metabolized by an enzyme Monoamine Oxidase Type B and its ability to cross the blood-brain barrier is partially limited. Because of these reasons, the activity of phenylethylamine gets compromised in the body and maximum results are not achieved.
In order to eradicate these drawbacks, an effective derivative of phenylethylamine is created called as N-methyl-B-phenylethylamine HCL. This compound is formed by adding a methyl group on the beta carbon of phenylethylamine. Because of this methylation, the pharmacokinetic properties of phenylethylamine are changed and its potency is increased. This new compound easily crosses the blood brain barrier and repels the oxidation caused by the enzyme Type B Monoamine Oxidase. Because of this reason, it remains active in the body for a long time and effectively causes maximum lipolysis, weight loss and mood regulation in an individual.
However, some adverse effects can be observed if these compounds are consumed in more than the required doses. Hence, these compounds should only be consumed in recommended doses after proper consultation with a registered medical practitioner to ensure maximum safety and efficacy.